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Husain, A.
- Synthesis of Some New Prodrugs of Sulphonamides and Studies on Their Antimicrobial and Anti-Inflammatory Action
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1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi, 110 062, IN
1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi, 110 062, IN
Source
Scientia Pharmaceutica, Vol 70, No 3 (2002), Pagination: 277-286Abstract
Various amide-based prodrugs of sulphonamides have been synthesised by condensing appropriate sulphonamide moiety with different β-aroyl propionic acids. All the compounds have been evaluated for their antimicrobial and anti-inflammatory activities. Their structures were established on the basis of elemental analysis, 1H NMR and Mass spectral data. Some of these compounds were found to have significant activity.Keywords
Sulphonamides, Prodrugs, Amides, Anti-Inflammatory, Antimicrobial
References
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- Synthesis and Antibacterial Evaluation of New Flavonoid Derivatives from 4,6-Diacetyl Resorcinol
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110 062, IN
1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110 062, IN
Source
Scientia Pharmaceutica, Vol 70, No 3 (2002), Pagination: 287-294Abstract
In order to check the antibacterial potential of bischalcones derived from 4,6-diacetyl resorcinol, a number of chalcone derivatives were synthesized by condensation with appropriate aromatic aldehydes. Out of these compounds 3b-i, 4a and 4b showed a good antibacterial activity. Methylation of the two chelated hydroxyls reduced the activity. However, oxidative cyclization of 3a and 3b resulted in compounds 4a and 4b which were found to be considerably active. The alternative method of synthesis of 4a and 4b via Baker-Venkatararnan rearrangement did not succeed.Keywords
Flavones, Bischalcones, Resorcinol, AntibacterialReferences
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- Performance Evaluation of Private Clouds:OpenStack Vs Eucalyptus
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Authors
Affiliations
1 Department of Computer Engineering, Aligarh Muslim University, Aligarh, Uttar Pradesh, IN
1 Department of Computer Engineering, Aligarh Muslim University, Aligarh, Uttar Pradesh, IN
Source
International Journal of Distributed and Cloud Computing, Vol 6, No 1 (2018), Pagination: 29-36Abstract
With the rapid growth of cloud infrastructure in the organizations, more applications are dependent on the quality of services like network, disk, memory, processor. Due to this, many organizations drift towards choosing right cloud for deploying the application which caters to user’s needs. Currently, opensource cloud platforms (OpenStack, Eucalyptus, Cloudstack, Opennebula etc) are gaining a lot of popularity that establishes private cloud with low cost. But it is difficult for organizations to choose a platform suitable for hosting web application or running virtual machines for high availability. This paper focuses on choosing right cloud platform for network, disk, processor, and memory in running application specific to user’s need. The efficacy of our method is validated through a series of experiments which consists of benchmarking the performance of OpenStack and Eucalyptus opensource private clouds. The experimental result shows that Eucalyptus cloud performs better for Network, Memory and Processing operations while OpenStack cloud performs better for Disk I/O operations.Keywords
Benchmarks, Cloud, Eucalyptus, OpenStack.References
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